discuss mood stabilizers
Assignment:
Construct a 5- to 6-page paper discussing
EACH of the four traditional mood stabilizer medications: carbamazepine, lamotrigine, lithium, and valproate products. Support your answers with
five (5) evidence-based, peer-reviewed scholarly literature.
Note: APA style format will apply.
Your paper should include the following for each:
· Proposed mechanism of action
· Baseline assessment, laboratory considerations, and frequency of ongoing labs and assessments
Note: Discuss the importance of assessment and labs.
· Special population considerations (birth assigned gender, age, other medical comorbidity considerations)
· FDA approval indications
· Typical dosing with discussion on therapeutic endpoints for psychiatric use
· Major drug–drug interaction considerations
· For each of these medications, please review potential drug–drug interactions listed below. Consider alternative dosing schedules, clinical implications for the drug interactions, additional patient education needed, any additional monitoring recommended, or collaboration needed with other medical professions (such as, primary care providers)
· Lamotrigine + Valproate
· Lamotrigine + Rifampin
· Valproate + Estrogen containing birth control.
· Valproate + Amitriptyline
· Lithium + Furosemide
· Lithium + Lisinopril
· Carbamazepine + Lurasidone
· Carbamazepine + Grapefruit juice
· Discuss the ethical, legal, and social implications related to prescribing bipolar and other related mood-disorder diagnoses therapy for patients.
Grading Rubric
For each of the four (4) traditional mood stabilizers, response includes proposed mechanism of action, baseline assessment, laboratory considerations, and frequency of ongoing. Discusses the importance of assessment and labs. Indication of special population considerations FDA approval. Discusses typical dosing with focus on therapeutic endpoints for psychiatric use of major drug-drug interaction considerations.
50 to >36.0 pts
· The response comprehensively and clearly describes all of the elements for each of the four (4) mood stabilizers.
Reviews the potential drug–drug interactions of the following: *Lamotrigine + Valproate; *Lamotrigine + Rifampin; *Valproate + Estrogen containing birth control; *Valproate + Amitriptyline; *Lithium + Furosemide; *Lithium + Lisinopril; *Carbamazepine + Lurasidone; *Carbamazepine + Grapefruit juice. Consider alternative dosing schedules, clinical implications for the drug interactions, additional patient education needed, any additional monitoring recommended, or collaboration needed with other medical professionals.
20 to >18.0 pts
· Reviews all seven to eight (7-8) of the potential drug-drug interactions with clear and accurate Discussion of alternative dosing, patient education, monitoring recommendation, and when to collaborate.
Discusses ethical, legal, and social implications related to prescribing these medications to patients.
10 to >7.0 pts
· The response accurately and clearly discusses ethical, legal and social implications. The response includes relevant, specific, and appropriate examples that fully support the Discussion.
The paper is succinct and is 5–6 pages. Five (5) evidence-based, peer- reviewed scholarly references outside of course resources.
5 to >4.0 pts
· The paper is succinct and is 5–6 pages. Five (5) evidence-based, peer- reviewed scholarly references outside of course resources
Written Expression and Formatting—Paragraph Development and Organization: Paragraphs make clear points that support well-developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused—neither long and rambling nor short and lacking substance. A clear and comprehensive purpose statement and introduction is provided which delineates all required criteria.
5 to >4.0 pts
· Paragraphs and sentences follow writing standards for flow, continuity, and clarity. A clear and comprehensive purpose statement, introduction, and conclusion is provided which delineates all required criteria.
Written Expression and Formatting—English writing standards: Correct grammar, mechanics, and proper punctuation.
5 to >4.0 pts
· Uses correct grammar, spelling, and punctuation with no errors.
Written Expression and Formatting: The paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, parenthetical/in-text citations, and reference list.
5 to >4.0 pts
· Uses correct APA format with no errors.
